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What is the basal lamina?

  1. A thick layer of muscle tissue

  2. A tough extracellular matrix separating epithelial cells from nerve tissue

  3. A collection of connective tissue cells

  4. A surgical term for the outer layer of skin

The correct answer is: A tough extracellular matrix separating epithelial cells from nerve tissue

The basal lamina refers to a specialized structure comprised of a thin layer of extracellular matrix that acts as a supportive foundation for epithelial tissues. It serves as a barrier that separates the epithelial cells from the underlying connective tissue, facilitating the exchange of nutrients and waste between the two. This structure is crucial for providing structural support and playing a role in cell signaling and tissue repair. The basal lamina is not a thick layer of muscle tissue, nor is it a surgical term for the outer layer of skin. While it influences cell behavior and maintenance of tissue integrity, it does not consist of a collection of connective tissue cells; rather, it is formed mainly by glycoproteins and collagen produced by epithelial cells. This understanding underscores the important role the basal lamina plays in overall tissue organization and function.